Breathing easier with AAT deficiency

Breathing easier.

Breathing Easier

Guangyu Zhu, Jia Chen, Jay Liu, Joseph S Brunzelle, Bo Huang, Nancy Wakeham, Simon Terzyan, Xuemei Li, Zihe Rao, Guangpu Li and Xuejun C Zhang* Crystallography Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Department of Biochemistry and Molecular Biol...

Not breathing easier.

were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessin...

EHPnet: Instructions for Breathing Easier

-The concanavalin A-mediated agglutinability of GR mouse mammary tumour cells changes during serial transplantation of the tumours. Hormonedependent cells in general have a lower agglutinability than hormone-independent cells. However, changes have also been observed in the histology of the tumours during serial transplantation, which as such may also alter the Con A-mediated agglutinability of...

Genetics of α1 Anti-Trypsin (AAT) Deficiency

Since the first description of alpha one antitrypsin deficiency (AATD) by Laurell and Eriksson in 1963, it has become a common but under-recognized genetic condition that predisposes to chronic obstructive pulmonary disease (COPD) and liver disease [1]. The prevalence of AATD is variable among different geographic areas and ethnic groups, where prevalence of the PiS allele is highest for countr...